Medical services are subject to increasing costs and are often unaffordable to the most, but also offer huge opportunities to the develop of mankind. Service performance needs enhancement and increased improvement. This session wants to focus on medicine. It wants to offer a platform for the improvement of health services.  These services are often fragmented and constrained by a disciplinary divide; scientific knowledge seems to still fail in contributing to solve people’s problems. The reductionism prevailing in modern biology and medicine has reached the "evolutionary bottom", finally decomposing biosystems into the most elementary parts – atoms and molecules. Further development of biomedicine  with the contribution of nano- bio-, information, cognitive - and Social (NBICS) technologies in the context of the latest industrial revolution (industry 4.0) is possible on the way of evolutionary rise in the levels of organization of biosystems and the return of wholeness in biomedical approaches and theories, i.e. in the framework of system biology and medicine.